000 02425 a2200709 4500
005 20250516202300.0
264 0 _c20141105
008 201411s 0 0 eng d
022 _a1946-6242
024 7 _a10.1126/scitranslmed.3007790
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSpencer, Andrew G
245 0 0 _aIntestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans.
_h[electronic resource]
260 _bScience translational medicine
_cMar 2014
300 _a227ra36 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial
650 0 4 _aAlbuminuria
_xcomplications
650 0 4 _aAngiotensin-Converting Enzyme Inhibitors
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aBlood Pressure
_xdrug effects
650 0 4 _aDisease Models, Animal
650 0 4 _aDogs
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aElectrolytes
_xurine
650 0 4 _aEnalapril
_xpharmacology
650 0 4 _aFeces
650 0 4 _aHealthy Volunteers
650 0 4 _aHumans
650 0 4 _aHypertrophy
650 0 4 _aIntestinal Mucosa
_xmetabolism
650 0 4 _aIntestines
_xdrug effects
650 0 4 _aIsoquinolines
_xadministration & dosage
650 0 4 _aKidney
_xdrug effects
650 0 4 _aMale
650 0 4 _aMyocardium
_xmetabolism
650 0 4 _aNephrectomy
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aRenal Insufficiency, Chronic
_xcomplications
650 0 4 _aSodium
_xmetabolism
650 0 4 _aSodium Chloride, Dietary
_xadministration & dosage
650 0 4 _aSodium-Hydrogen Exchanger 3
650 0 4 _aSodium-Hydrogen Exchangers
_xantagonists & inhibitors
650 0 4 _aSulfonamides
_xadministration & dosage
700 1 _aLabonte, Eric D
700 1 _aRosenbaum, David P
700 1 _aPlato, Craig F
700 1 _aCarreras, Christopher W
700 1 _aLeadbetter, Michael R
700 1 _aKozuka, Kenji
700 1 _aKohler, Jill
700 1 _aKoo-McCoy, Samantha
700 1 _aHe, Limin
700 1 _aBell, Noah
700 1 _aTabora, Jocelyn
700 1 _aJoly, Kristin M
700 1 _aNavre, Marc
700 1 _aJacobs, Jeffrey W
700 1 _aCharmot, Dominique
773 0 _tScience translational medicine
_gvol. 6
_gno. 227
_gp. 227ra36
856 4 0 _uhttps://doi.org/10.1126/scitranslmed.3007790
_zAvailable from publisher's website
999 _c23633846
_d23633846