000			02271 a2200697 4500
005			20250516200217.0
264		0	_c20141021
008			201410s 0 0 eng d
022			_a2041-4889
024	7		_a10.1038/cddis.2014.54 _2doi
040			_aNLM _beng _cNLM
100	1		_aCheng, J
245	0	0	_aA small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways. _h[electronic resource]
260			_bCell death & disease _cFeb 2014
300			_ae1079 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aActive Transport, Cell Nucleus _xdrug effects
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xpharmacology
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aCell Line, Tumor
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDrug Resistance, Neoplasm
650	0	4	_aEnzyme Activation
650	0	4	_aEnzyme Inhibitors _xpharmacology
650	0	4	_aFemale
650	0	4	_aHEK293 Cells
650	0	4	_aHumans
650	0	4	_aJNK Mitogen-Activated Protein Kinases _xantagonists & inhibitors
650	0	4	_aMice
650	0	4	_aMice, Nude
650	0	4	_aMutation
650	0	4	_aNeuroblastoma _xdrug therapy
650	0	4	_aProtein Kinase Inhibitors _xpharmacology
650	0	4	_aSignal Transduction _xdrug effects
650	0	4	_aTime Factors
650	0	4	_aTransfection
650	0	4	_aTumor Burden _xdrug effects
650	0	4	_aTumor Suppressor Protein p53 _xgenetics
650	0	4	_aUbiquitin-Conjugating Enzymes _xantagonists & inhibitors
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aFan, Y-H
700	1		_aXu, X
700	1		_aZhang, H
700	1		_aDou, J
700	1		_aTang, Y
700	1		_aZhong, X
700	1		_aRojas, Y
700	1		_aYu, Y
700	1		_aZhao, Y
700	1		_aVasudevan, S A
700	1		_aZhang, H
700	1		_aNuchtern, J G
700	1		_aKim, E S
700	1		_aChen, X
700	1		_aLu, F
700	1		_aYang, J
773	0		_tCell death & disease _gvol. 5 _gp. e1079
856	4	0	_uhttps://doi.org/10.1038/cddis.2014.54 _zAvailable from publisher's website
999			_c23573966 _d23573966