| 000 | 01622 a2200397 4500 | ||
|---|---|---|---|
| 005 | 20250516200141.0 | ||
| 264 | 0 | _c20140521 | |
| 008 | 201405s 0 0 eng d | ||
| 022 | _a1083-351X | ||
| 024 | 7 |
_a10.1074/jbc.M114.551143 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aJoshi, Poorval M | |
| 245 | 0 | 0 |
_aOvarian cancer-associated mutations disable catalytic activity of CDK12, a kinase that promotes homologous recombination repair and resistance to cisplatin and poly(ADP-ribose) polymerase inhibitors. _h[electronic resource] |
| 260 |
_bThe Journal of biological chemistry _cMar 2014 |
||
| 300 |
_a9247-53 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aBiocatalysis _xdrug effects |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 |
_aCisplatin _xpharmacology |
| 650 | 0 | 4 |
_aCross-Linking Reagents _xpharmacology |
| 650 | 0 | 4 |
_aCyclin-Dependent Kinases _xdeficiency |
| 650 | 0 | 4 |
_aDNA Repair _xgenetics |
| 650 | 0 | 4 |
_aDrug Resistance, Neoplasm _xgenetics |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xpharmacology |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aHomologous Recombination _xdrug effects |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 |
_aOvarian Neoplasms _xenzymology |
| 650 | 0 | 4 | _aPoly(ADP-ribose) Polymerase Inhibitors |
| 700 | 1 | _aSutor, Shari L | |
| 700 | 1 | _aHuntoon, Catherine J | |
| 700 | 1 | _aKarnitz, Larry M | |
| 773 | 0 |
_tThe Journal of biological chemistry _gvol. 289 _gno. 13 _gp. 9247-53 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1074/jbc.M114.551143 _zAvailable from publisher's website |
| 999 |
_c23572042 _d23572042 |
||