000 02072 a2200553 4500
005 20250516183946.0
264 0 _c20140303
008 201403s 0 0 eng d
022 _a1521-0103
024 7 _a10.1124/jpet.113.209643
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aThurner, Patrick
245 0 0 _aMechanism of hERG channel block by the psychoactive indole alkaloid ibogaine.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cFeb 2014
300 _a346-58 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Substitution
650 0 4 _aBinding Sites
_xdrug effects
650 0 4 _aCell Line
650 0 4 _aCytosol
_xmetabolism
650 0 4 _aERG1 Potassium Channel
650 0 4 _aEther-A-Go-Go Potassium Channels
_xantagonists & inhibitors
650 0 4 _aExcitatory Amino Acid Antagonists
_xadverse effects
650 0 4 _aHallucinogens
_xadverse effects
650 0 4 _aHumans
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aIbogaine
_xadverse effects
650 0 4 _aIon Channel Gating
_xdrug effects
650 0 4 _aKinetics
650 0 4 _aMembrane Potentials
_xdrug effects
650 0 4 _aMembrane Transport Modulators
_xpharmacology
650 0 4 _aMolecular Conformation
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMutant Proteins
_xagonists
650 0 4 _aNarcotic Antagonists
_xadverse effects
650 0 4 _aNerve Tissue Proteins
_xantagonists & inhibitors
650 0 4 _aRecombinant Proteins
_xchemistry
700 1 _aStary-Weinzinger, Anna
700 1 _aGafar, Hend
700 1 _aGawali, Vaibhavkumar S
700 1 _aKudlacek, Oliver
700 1 _aZezula, Juergen
700 1 _aHilber, Karlheinz
700 1 _aBoehm, Stefan
700 1 _aSandtner, Walter
700 1 _aKoenig, Xaver
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 348
_gno. 2
_gp. 346-58
856 4 0 _uhttps://doi.org/10.1124/jpet.113.209643
_zAvailable from publisher's website
999 _c23337696
_d23337696