000 01710 a2200481 4500
005 20250516181737.0
264 0 _c20140430
008 201404s 0 0 eng d
022 _a1476-5551
024 7 _a10.1038/leu.2013.345
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKaindl, U
245 0 0 _aBlocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia.
_h[electronic resource]
260 _bLeukemia
_cMar 2014
300 _a600-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aChild
650 0 4 _aChromatin Immunoprecipitation
650 0 4 _aCore Binding Factor Alpha 2 Subunit
_xgenetics
650 0 4 _aHumans
650 0 4 _aImidazoles
_xpharmacology
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aPrecursor Cell Lymphoblastic Leukemia-Lymphoma
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-ets
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-mdm2
_xgenetics
650 0 4 _aReal-Time Polymerase Chain Reaction
650 0 4 _aRepressor Proteins
_xgenetics
650 0 4 _aSignal Transduction
650 0 4 _aTranscription, Genetic
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
650 0 4 _aETS Translocation Variant 6 Protein
700 1 _aMorak, M
700 1 _aPortsmouth, C
700 1 _aMecklenbräuker, A
700 1 _aKauer, M
700 1 _aZeginigg, M
700 1 _aAttarbaschi, A
700 1 _aHaas, O A
700 1 _aPanzer-Grümayer, R
773 0 _tLeukemia
_gvol. 28
_gno. 3
_gp. 600-8
856 4 0 _uhttps://doi.org/10.1038/leu.2013.345
_zAvailable from publisher's website
999 _c23273980
_d23273980