000 02032 a2200541 4500
005 20250516181454.0
264 0 _c20140820
008 201408s 0 0 eng d
022 _a1873-3476
024 7 _a10.1016/j.ijpharm.2013.11.004
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBédouet, Laurent
245 0 0 _aSynthesis of hydrophilic intra-articular microspheres conjugated to ibuprofen and evaluation of anti-inflammatory activity on articular explants.
_h[electronic resource]
260 _bInternational journal of pharmaceutics
_cJan 2014
300 _a51-61 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAnti-Inflammatory Agents, Non-Steroidal
_xadministration & dosage
650 0 4 _aCartilage, Articular
_xdrug effects
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aCyclooxygenase Inhibitors
_xpharmacology
650 0 4 _aDelayed-Action Preparations
650 0 4 _aDialysis
650 0 4 _aDinoprostone
_xmetabolism
650 0 4 _aHydrolysis
650 0 4 _aIbuprofen
_xadministration & dosage
650 0 4 _aInjections, Intra-Articular
650 0 4 _aL-Lactate Dehydrogenase
_xmetabolism
650 0 4 _aLactic Acid
650 0 4 _aLipopolysaccharides
_xpharmacology
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aMicrospheres
650 0 4 _aOrgan Culture Techniques
650 0 4 _aParticle Size
650 0 4 _aPolyethylene Glycols
650 0 4 _aPolyglycolic Acid
650 0 4 _aPolylactic Acid-Polyglycolic Acid Copolymer
650 0 4 _aProstaglandin-Endoperoxide Synthases
_xmetabolism
650 0 4 _aSheep
650 0 4 _aSynovial Membrane
_xdrug effects
700 1 _aMoine, Laurence
700 1 _aPascale, Florentina
700 1 _aNguyen, Van-Nga
700 1 _aLabarre, Denis
700 1 _aLaurent, Alexandre
773 0 _tInternational journal of pharmaceutics
_gvol. 459
_gno. 1-2
_gp. 51-61
856 4 0 _uhttps://doi.org/10.1016/j.ijpharm.2013.11.004
_zAvailable from publisher's website
999 _c23265579
_d23265579