000 | 01905 a2200517 4500 | ||
---|---|---|---|
005 | 20250516180835.0 | ||
264 | 0 | _c20140919 | |
008 | 201409s 0 0 eng d | ||
022 | _a1768-3254 | ||
024 | 7 |
_a10.1016/j.ejmech.2013.10.038 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aKovács, Dóra | |
245 | 0 | 0 |
_aAn efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase. _h[electronic resource] |
260 |
_bEuropean journal of medicinal chemistry _c2013 |
||
300 |
_a649-60 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAndrostenes _xchemical synthesis |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
650 | 0 | 4 | _aCell Line, Tumor |
650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
650 | 0 | 4 | _aCyclization |
650 | 0 | 4 | _aDehydration |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
650 | 0 | 4 |
_aEnzyme Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aHeLa Cells |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMCF-7 Cells |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMolecular Conformation |
650 | 0 | 4 |
_aOximes _xchemistry |
650 | 0 | 4 | _aRats |
650 | 0 | 4 | _aRats, Wistar |
650 | 0 | 4 |
_aSteroid 17-alpha-Hydroxylase _xantagonists & inhibitors |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aTestis _xenzymology |
700 | 1 | _aWölfling, János | |
700 | 1 | _aSzabó, Nikoletta | |
700 | 1 | _aSzécsi, Mihály | |
700 | 1 | _aKovács, Ida | |
700 | 1 | _aZupkó, István | |
700 | 1 | _aFrank, Eva | |
773 | 0 |
_tEuropean journal of medicinal chemistry _gvol. 70 _gp. 649-60 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.ejmech.2013.10.038 _zAvailable from publisher's website |
999 |
_c23247951 _d23247951 |