| 000 | 01685 a2200445 4500 | ||
|---|---|---|---|
| 005 | 20250516180358.0 | ||
| 264 | 0 | _c20140929 | |
| 008 | 201409s 0 0 eng d | ||
| 022 | _a1538-8514 | ||
| 024 | 7 |
_a10.1158/1535-7163.MCT-13-0479 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aThomas, Nisha E | |
| 245 | 0 | 0 |
_aReversible action of diaminothiazoles in cancer cells is implicated by the induction of a fast conformational change of tubulin and suppression of microtubule dynamics. _h[electronic resource] |
| 260 |
_bMolecular cancer therapeutics _cJan 2014 |
||
| 300 |
_a179-89 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 |
_aColchicine _xadministration & dosage |
| 650 | 0 | 4 |
_aColonic Neoplasms _xdrug therapy |
| 650 | 0 | 4 | _aHCT116 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aHydrogen Bonding |
| 650 | 0 | 4 |
_aMicrotubules _xdrug effects |
| 650 | 0 | 4 |
_aMitosis _xdrug effects |
| 650 | 0 | 4 | _aMolecular Dynamics Simulation |
| 650 | 0 | 4 |
_aProtein Conformation _xdrug effects |
| 650 | 0 | 4 |
_aThiazoles _xadministration & dosage |
| 650 | 0 | 4 |
_aTubulin _xchemistry |
| 700 | 1 | _aThamkachy, Reshma | |
| 700 | 1 | _aSivakumar, Krishnankutty C | |
| 700 | 1 | _aSreedevi, Krishnakumar J | |
| 700 | 1 | _aLouis, Xavier Lieben | |
| 700 | 1 | _aThomas, Sannu A | |
| 700 | 1 | _aKumar, Rohith | |
| 700 | 1 | _aRajasekharan, Kallikat N | |
| 700 | 1 | _aCassimeris, Lynne | |
| 700 | 1 | _aSengupta, Suparna | |
| 773 | 0 |
_tMolecular cancer therapeutics _gvol. 13 _gno. 1 _gp. 179-89 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1158/1535-7163.MCT-13-0479 _zAvailable from publisher's website |
| 999 |
_c23233794 _d23233794 |
||