000 02145 a2200565 4500
005 20250516175957.0
264 0 _c20140318
008 201403s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm4008517
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJurutka, Peter W
245 0 0 _aModeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254).
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cNov 2013
300 _a8432-54 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aCoumaric Acids
_xchemical synthesis
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHumans
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aRetinoid X Receptors
_xagonists
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTetrahydronaphthalenes
_xchemical synthesis
700 1 _aKaneko, Ichiro
700 1 _aYang, Joanna
700 1 _aBhogal, Jaskaran S
700 1 _aSwierski, Johnathon C
700 1 _aTabacaru, Christa R
700 1 _aMontano, Luis A
700 1 _aHuynh, Chanh C
700 1 _aJama, Rabia A
700 1 _aMahelona, Ryan D
700 1 _aSarnowski, Joseph T
700 1 _aMarcus, Lisa M
700 1 _aQuezada, Alexis
700 1 _aLemming, Brittney
700 1 _aTedesco, Maria A
700 1 _aFischer, Audra J
700 1 _aMohamed, Said A
700 1 _aZiller, Joseph W
700 1 _aMa, Ning
700 1 _aGray, Geoffrey M
700 1 _avan der Vaart, Arjan
700 1 _aMarshall, Pamela A
700 1 _aWagner, Carl E
773 0 _tJournal of medicinal chemistry
_gvol. 56
_gno. 21
_gp. 8432-54
856 4 0 _uhttps://doi.org/10.1021/jm4008517
_zAvailable from publisher's website
999 _c23221619
_d23221619