000 02019 a2200553 4500
005 20250516175005.0
264 0 _c20140515
008 201405s 0 0 eng d
022 _a1097-0215
024 7 _a10.1002/ijc.28521
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aNeumann, Jennifer
245 0 0 _aThe natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints.
_h[electronic resource]
260 _bInternational journal of cancer
_cApr 2014
300 _a1991-2002 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aAtaxia Telangiectasia Mutated Proteins
_xdrug effects
650 0 4 _aBenzofurans
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCheckpoint Kinase 1
650 0 4 _aCheckpoint Kinase 2
_xgenetics
650 0 4 _aDNA Damage
_xdrug effects
650 0 4 _aHCT116 Cells
650 0 4 _aHT29 Cells
650 0 4 _aHep G2 Cells
650 0 4 _aHumans
650 0 4 _aJurkat Cells
650 0 4 _aLeukemia
_xdrug therapy
650 0 4 _aMCF-7 Cells
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aPlant Extracts
_xpharmacology
650 0 4 _aProtein Biosynthesis
_xdrug effects
650 0 4 _aProtein Kinases
_xgenetics
650 0 4 _aRNA Interference
650 0 4 _aRNA, Small Interfering
650 0 4 _aS Phase Cell Cycle Checkpoints
_xdrug effects
650 0 4 _aT-Lymphocytes
_xdrug effects
650 0 4 _acdc25 Phosphatases
_xbiosynthesis
700 1 _aBoerries, Melanie
700 1 _aKöhler, Rebecca
700 1 _aGiaisi, Marco
700 1 _aKrammer, Peter H
700 1 _aBusch, Hauke
700 1 _aLi-Weber, Min
773 0 _tInternational journal of cancer
_gvol. 134
_gno. 8
_gp. 1991-2002
856 4 0 _uhttps://doi.org/10.1002/ijc.28521
_zAvailable from publisher's website
999 _c23194697
_d23194697