000 01504 a2200409 4500
005 20250516173108.0
264 0 _c20140514
008 201405s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2013.09.027
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKang, Bo-Rui
245 0 0 _aDiscovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cNov 2013
300 _a6956-64 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xchemistry
650 0 4 _aBinding Sites
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aErbB Receptors
_xantagonists & inhibitors
650 0 4 _aHumans
650 0 4 _aIsoquinolines
_xchemistry
650 0 4 _aMolecular Docking Simulation
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xchemistry
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aStructure-Activity Relationship
700 1 _aShan, Ai-Lin
700 1 _aLi, Yi-Ping
700 1 _aXu, Jing
700 1 _aLu, She-Min
700 1 _aZhang, San-Qi
773 0 _tBioorganic & medicinal chemistry
_gvol. 21
_gno. 22
_gp. 6956-64
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2013.09.027
_zAvailable from publisher's website
999 _c23142180
_d23142180