000 02687 a2200829 4500
005 20250516172804.0
264 0 _c20140310
008 201403s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm400731m
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDonnell, Andrew F
245 0 0 _aBenzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cOct 2013
300 _a7772-87 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAlanine
_xanalogs & derivatives
650 0 4 _aAnimals
650 0 4 _aAntibodies, Monoclonal
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBlotting, Western
650 0 4 _aCaspase 3
_xmetabolism
650 0 4 _aCaspase 7
_xmetabolism
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCrystallography, X-Ray
650 0 4 _aFemale
650 0 4 _aHeterocyclic Compounds
_xchemical synthesis
650 0 4 _aHumans
650 0 4 _aInhibitor of Apoptosis Proteins
_xantagonists & inhibitors
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aModels, Chemical
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aOxazepines
_xchemical synthesis
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aRats
650 0 4 _aUbiquitin-Protein Ligases
650 0 4 _aX-Linked Inhibitor of Apoptosis Protein
_xantagonists & inhibitors
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aMichoud, Christophe
700 1 _aRupert, Kenneth C
700 1 _aHan, Xiaochun
700 1 _aAguilar, Douglas
700 1 _aFrank, Karl B
700 1 _aFretland, Adrian J
700 1 _aGao, Lin
700 1 _aGoggin, Barry
700 1 _aHogg, J Heather
700 1 _aHong, Kyoungja
700 1 _aJanson, Cheryl A
700 1 _aKester, Robert F
700 1 _aKong, Norman
700 1 _aLe, Kang
700 1 _aLi, Shirley
700 1 _aLiang, Weiling
700 1 _aLombardo, Louis J
700 1 _aLou, Yan
700 1 _aLukacs, Christine M
700 1 _aMischke, Steven
700 1 _aMoliterni, John A
700 1 _aPolonskaia, Ann
700 1 _aSchutt, Andrew D
700 1 _aSolis, Dave S
700 1 _aSpecian, Anthony
700 1 _aTaylor, Robert T
700 1 _aWeisel, Martin
700 1 _aRemiszewski, Stacy W
773 0 _tJournal of medicinal chemistry
_gvol. 56
_gno. 20
_gp. 7772-87
856 4 0 _uhttps://doi.org/10.1021/jm400731m
_zAvailable from publisher's website
999 _c23133271
_d23133271