000 01427 a2200409 4500
005 20250511233101.0
264 0 _c19900222
008 199002s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00163a006
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSliskovic, D R
245 0 0 _aInhibitors of cholesterol biosynthesis. 2. 1,3,5-trisubstituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJan 1990
300 _a31-8 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAnimals
650 0 4 _aChemical Phenomena
650 0 4 _aChemistry
650 0 4 _aCholesterol
_xbiosynthesis
650 0 4 _aHydroxymethylglutaryl-CoA Reductase Inhibitors
650 0 4 _aLactones
650 0 4 _aLiver
_xenzymology
650 0 4 _aLovastatin
_xanalogs & derivatives
650 0 4 _aMevalonic Acid
_xanalogs & derivatives
650 0 4 _aMolecular Conformation
650 0 4 _aMolecular Structure
650 0 4 _aPyrazoles
_xchemical synthesis
650 0 4 _aRats
650 0 4 _aStructure-Activity Relationship
700 1 _aRoth, B D
700 1 _aWilson, M W
700 1 _aHoefle, M L
700 1 _aNewton, R S
773 0 _tJournal of medicinal chemistry
_gvol. 33
_gno. 1
_gp. 31-8
856 4 0 _uhttps://doi.org/10.1021/jm00163a006
_zAvailable from publisher's website
999 _c2302104
_d2302104