000 01665 a2200445 4500
005 20250516162047.0
264 0 _c20140519
008 201405s 0 0 eng d
022 _a1538-8514
024 7 _a10.1158/1535-7163.MCT-12-1093
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMereniuk, Todd R
245 0 0 _aSynthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_cOct 2013
300 _a2135-44 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aApoptosis
_xgenetics
650 0 4 _aCell Line, Tumor
650 0 4 _aDNA Breaks, Double-Stranded
650 0 4 _aDNA Repair
_xgenetics
650 0 4 _aDNA Repair Enzymes
_xantagonists & inhibitors
650 0 4 _aGene Knockout Techniques
650 0 4 _aHCT116 Cells
650 0 4 _aHumans
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aPTEN Phosphohydrolase
_xgenetics
650 0 4 _aPhosphotransferases (Alcohol Group Acceptor)
_xantagonists & inhibitors
650 0 4 _aRNA, Small Interfering
650 0 4 _aRadiation Tolerance
_xdrug effects
700 1 _aEl Gendy, Mohamed A M
700 1 _aMendes-Pereira, Ana M
700 1 _aLord, Christopher J
700 1 _aGhosh, Sunita
700 1 _aFoley, Edan
700 1 _aAshworth, Alan
700 1 _aWeinfeld, Michael
773 0 _tMolecular cancer therapeutics
_gvol. 12
_gno. 10
_gp. 2135-44
856 4 0 _uhttps://doi.org/10.1158/1535-7163.MCT-12-1093
_zAvailable from publisher's website
999 _c22944993
_d22944993