| 000 | 02919 a2200841 4500 | ||
|---|---|---|---|
| 005 | 20250516162022.0 | ||
| 264 | 0 | _c20131104 | |
| 008 | 201311s 0 0 eng d | ||
| 022 | _a1091-6490 | ||
| 024 | 7 |
_a10.1073/pnas.1302725110 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aMerchant, Mark | |
| 245 | 0 | 0 |
_aMonovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent. _h[electronic resource] |
| 260 |
_bProceedings of the National Academy of Sciences of the United States of America _cAug 2013 |
||
| 300 |
_aE2987-96 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. | ||
| 650 | 0 | 4 | _aAmino Acid Sequence |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntibodies, Monoclonal _xchemistry |
| 650 | 0 | 4 |
_aAntibodies, Monoclonal, Humanized _xchemistry |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemistry |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 | _aCrystallography, X-Ray |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 |
_aHepatocyte Growth Factor _xchemistry |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImmunoglobulin Fab Fragments _xchemistry |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Inbred BALB C |
| 650 | 0 | 4 | _aMice, Inbred C3H |
| 650 | 0 | 4 | _aMice, Nude |
| 650 | 0 | 4 | _aMice, SCID |
| 650 | 0 | 4 | _aMice, Transgenic |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Sequence Data |
| 650 | 0 | 4 |
_aNeoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aProtein Binding _xdrug effects |
| 650 | 0 | 4 | _aProtein Structure, Tertiary |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins c-met _xantagonists & inhibitors |
| 650 | 0 | 4 | _aSequence Homology, Amino Acid |
| 650 | 0 | 4 | _aXenograft Model Antitumor Assays |
| 700 | 1 | _aMa, Xiaolei | |
| 700 | 1 | _aMaun, Henry R | |
| 700 | 1 | _aZheng, Zhong | |
| 700 | 1 | _aPeng, Jing | |
| 700 | 1 | _aRomero, Mally | |
| 700 | 1 | _aHuang, Arthur | |
| 700 | 1 | _aYang, Nai-ying | |
| 700 | 1 | _aNishimura, Merry | |
| 700 | 1 | _aGreve, Joan | |
| 700 | 1 | _aSantell, Lydia | |
| 700 | 1 | _aZhang, Yu-Wen | |
| 700 | 1 | _aSu, Yanli | |
| 700 | 1 | _aKaufman, Dafna W | |
| 700 | 1 | _aBilleci, Karen L | |
| 700 | 1 | _aMai, Elaine | |
| 700 | 1 | _aMoffat, Barbara | |
| 700 | 1 | _aLim, Amy | |
| 700 | 1 | _aDuenas, Eileen T | |
| 700 | 1 | _aPhillips, Heidi S | |
| 700 | 1 | _aXiang, Hong | |
| 700 | 1 | _aYoung, Judy C | |
| 700 | 1 | _aVande Woude, George F | |
| 700 | 1 | _aDennis, Mark S | |
| 700 | 1 | _aReilly, Dorothea E | |
| 700 | 1 | _aSchwall, Ralph H | |
| 700 | 1 | _aStarovasnik, Melissa A | |
| 700 | 1 | _aLazarus, Robert A | |
| 700 | 1 | _aYansura, Daniel G | |
| 773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 110 _gno. 32 _gp. E2987-96 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.1302725110 _zAvailable from publisher's website |
| 999 |
_c22943731 _d22943731 |
||