000 01931 a2200541 4500
005 20250516160513.0
264 0 _c20141028
008 201410s 0 0 eng d
022 _a1432-0738
024 7 _a10.1007/s00204-013-1085-6
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhang, Yi
245 0 0 _aV8, a newly synthetic flavonoid, induces apoptosis through ROS-mediated ER stress pathway in hepatocellular carcinoma.
_h[electronic resource]
260 _bArchives of toxicology
_cJan 2014
300 _a97-107 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCarcinoma, Hepatocellular
_xdrug therapy
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aEndoplasmic Reticulum Chaperone BiP
650 0 4 _aEndoplasmic Reticulum Stress
_xdrug effects
650 0 4 _aFemale
650 0 4 _aFlavanones
_xchemistry
650 0 4 _aFlavones
_xchemical synthesis
650 0 4 _aHep G2 Cells
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aLiver Neoplasms
_xdrug therapy
650 0 4 _aMembrane Potential, Mitochondrial
_xdrug effects
650 0 4 _aMice
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTranscription Factor CHOP
_xgenetics
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aZhao, Li
700 1 _aLi, Xin
700 1 _aWang, Yajing
700 1 _aYao, Jing
700 1 _aWang, Hu
700 1 _aLi, Fanni
700 1 _aLi, Zhiyu
700 1 _aGuo, Qinglong
773 0 _tArchives of toxicology
_gvol. 88
_gno. 1
_gp. 97-107
856 4 0 _uhttps://doi.org/10.1007/s00204-013-1085-6
_zAvailable from publisher's website
999 _c22900576
_d22900576