| 000 | 01512 a2200409 4500 | ||
|---|---|---|---|
| 005 | 20250516160438.0 | ||
| 264 | 0 | _c20140321 | |
| 008 | 201403s 0 0 eng d | ||
| 022 | _a1549-960X | ||
| 024 | 7 |
_a10.1021/ci400178h _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aTosso, Rodrigo D | |
| 245 | 0 | 0 |
_aMolecular modeling study of dihydrofolate reductase inhibitors. Molecular dynamics simulations, quantum mechanical calculations, and experimental corroboration. _h[electronic resource] |
| 260 |
_bJournal of chemical information and modeling _cAug 2013 |
||
| 300 |
_a2018-32 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aElectrons |
| 650 | 0 | 4 |
_aFolic Acid Antagonists _xpharmacology |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMolecular Dynamics Simulation |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aQuantum Theory |
| 650 | 0 | 4 | _aReproducibility of Results |
| 650 | 0 | 4 |
_aTetrahydrofolate Dehydrogenase _xchemistry |
| 650 | 0 | 4 | _aThermodynamics |
| 700 | 1 | _aAndujar, Sebastian A | |
| 700 | 1 | _aGutierrez, Lucas | |
| 700 | 1 | _aAngelina, Emilio | |
| 700 | 1 | _aRodríguez, Ricaurte | |
| 700 | 1 | _aNogueras, Manuel | |
| 700 | 1 | _aBaldoni, Héctor | |
| 700 | 1 | _aSuvire, Fernando D | |
| 700 | 1 | _aCobo, Justo | |
| 700 | 1 | _aEnriz, Ricardo D | |
| 773 | 0 |
_tJournal of chemical information and modeling _gvol. 53 _gno. 8 _gp. 2018-32 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/ci400178h _zAvailable from publisher's website |
| 999 |
_c22898990 _d22898990 |
||