000 01540 a2200385 4500
005 20250516155022.0
264 0 _c20140624
008 201406s 0 0 eng d
022 _a1521-009X
024 7 _a10.1124/dmd.113.052241
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCallegari, Ernesto
245 0 0 _aDrug metabolites as cytochrome p450 inhibitors: a retrospective analysis and proposed algorithm for evaluation of the pharmacokinetic interaction potential of metabolites in drug discovery and development.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_cDec 2013
300 _a2047-55 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAlgorithms
650 0 4 _aArea Under Curve
650 0 4 _aBiotransformation
_xphysiology
650 0 4 _aCytochrome P-450 Enzyme Inhibitors
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aDatabases, Factual
650 0 4 _aDrug Discovery
_xmethods
650 0 4 _aDrug Interactions
_xphysiology
650 0 4 _aHumans
650 0 4 _aPharmaceutical Preparations
_xmetabolism
650 0 4 _aRetrospective Studies
700 1 _aKalgutkar, Amit S
700 1 _aLeung, Louis
700 1 _aObach, R Scott
700 1 _aPlowchalk, David R
700 1 _aTse, Susanna
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 41
_gno. 12
_gp. 2047-55
856 4 0 _uhttps://doi.org/10.1124/dmd.113.052241
_zAvailable from publisher's website
999 _c22858906
_d22858906