000 02047 a2200577 4500
005 20250516153830.0
264 0 _c20140320
008 201403s 0 0 eng d
022 _a1552-4604
024 7 _a10.1002/jcph.116
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHan, Tae H
245 0 0 _aCYP3A-mediated drug-drug interaction potential and excretion of brentuximab vedotin, an antibody-drug conjugate, in patients with CD30-positive hematologic malignancies.
_h[electronic resource]
260 _bJournal of clinical pharmacology
_cAug 2013
300 _a866-77 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aBrentuximab Vedotin
650 0 4 _aCross-Over Studies
650 0 4 _aCytochrome P-450 CYP3A
_xmetabolism
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
650 0 4 _aDrug Interactions
650 0 4 _aFeces
_xchemistry
650 0 4 _aFemale
650 0 4 _aHematologic Neoplasms
_xmetabolism
650 0 4 _aHumans
650 0 4 _aImmunoconjugates
_xadministration & dosage
650 0 4 _aKetoconazole
_xadministration & dosage
650 0 4 _aKi-1 Antigen
_ximmunology
650 0 4 _aMale
650 0 4 _aMidazolam
_xadministration & dosage
650 0 4 _aMiddle Aged
650 0 4 _aOligopeptides
_xmetabolism
650 0 4 _aRifampin
_xadministration & dosage
650 0 4 _aYoung Adult
700 1 _aGopal, Ajay K
700 1 _aRamchandren, Radhakrishnan
700 1 _aGoy, Andre
700 1 _aChen, Robert
700 1 _aMatous, Jeffrey V
700 1 _aCooper, Maureen
700 1 _aGrove, Laurie E
700 1 _aAlley, Stephen C
700 1 _aLynch, Carmel M
700 1 _aO'Connor, Owen A
773 0 _tJournal of clinical pharmacology
_gvol. 53
_gno. 8
_gp. 866-77
856 4 0 _uhttps://doi.org/10.1002/jcph.116
_zAvailable from publisher's website
999 _c22824428
_d22824428