000 01646 a2200433 4500
005 20250516152932.0
264 0 _c20140113
008 201401s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2013.05.020
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLovell, Kimberly M
245 0 0 _aN-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cJul 2013
300 _a3713-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAllosteric Regulation
_xdrug effects
650 0 4 _aAnimals
650 0 4 _aCentral Nervous System
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aMolecular Structure
650 0 4 _aPiperazines
_xchemical synthesis
650 0 4 _aRats
650 0 4 _aReceptors, Metabotropic Glutamate
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
700 1 _aFelts, Andrew S
700 1 _aRodriguez, Alice L
700 1 _aVenable, Daryl F
700 1 _aCho, Hyekyung P
700 1 _aMorrison, Ryan D
700 1 _aByers, Frank W
700 1 _aDaniels, J Scott
700 1 _aNiswender, Colleen M
700 1 _aConn, P Jeffrey
700 1 _aLindsley, Craig W
700 1 _aEmmitte, Kyle A
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 23
_gno. 13
_gp. 3713-8
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2013.05.020
_zAvailable from publisher's website
999 _c22798914
_d22798914