000			02151 a2200649 4500
005			20250516152850.0
264		0	_c20130628
008			201306s 0 0 eng d
022			_a1533-4406
024	7		_a10.1056/NEJMoa1215530 _2doi
040			_aNLM _beng _cNLM
100	1		_aAwad, Mark M
245	0	0	_aAcquired resistance to crizotinib from a mutation in CD74-ROS1. _h[electronic resource]
260			_bThe New England journal of medicine _cJun 2013
300			_a2395-401 p. _bdigital
500			_aPublication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAdenocarcinoma _xdrug therapy
650	0	4	_aCrizotinib
650	0	4	_aDrug Resistance _xgenetics
650	0	4	_aFatal Outcome
650	0	4	_aFemale
650	0	4	_aHumans
650	0	4	_aLung Neoplasms _xdrug therapy
650	0	4	_aMiddle Aged
650	0	4	_aMutation
650	0	4	_aProtein Conformation
650	0	4	_aProtein Kinase Inhibitors _xtherapeutic use
650	0	4	_aProtein-Tyrosine Kinases _xchemistry
650	0	4	_aProto-Oncogene Proteins _xchemistry
650	0	4	_aPyrazoles _xtherapeutic use
650	0	4	_aPyridines _xtherapeutic use
650	0	4	_aStructure-Activity Relationship
650	0	4	_aTranslocation, Genetic
700	1		_aKatayama, Ryohei
700	1		_aMcTigue, Michele
700	1		_aLiu, Wei
700	1		_aDeng, Ya-Li
700	1		_aBrooun, Alexei
700	1		_aFriboulet, Luc
700	1		_aHuang, Donghui
700	1		_aFalk, Matthew D
700	1		_aTimofeevski, Sergei
700	1		_aWilner, Keith D
700	1		_aLockerman, Elizabeth L
700	1		_aKhan, Tahsin M
700	1		_aMahmood, Sidra
700	1		_aGainor, Justin F
700	1		_aDigumarthy, Subba R
700	1		_aStone, James R
700	1		_aMino-Kenudson, Mari
700	1		_aChristensen, James G
700	1		_aIafrate, A John
700	1		_aEngelman, Jeffrey A
700	1		_aShaw, Alice T
773	0		_tThe New England journal of medicine _gvol. 368 _gno. 25 _gp. 2395-401
856	4	0	_uhttps://doi.org/10.1056/NEJMoa1215530 _zAvailable from publisher's website
999			_c22796834 _d22796834