000 01975 a2200541 4500
005 20250516151948.0
264 0 _c20140401
008 201404s 0 0 eng d
022 _a1538-8514
024 7 _a10.1158/1535-7163.MCT-12-1057
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhou, Binhua
245 0 0 _aDeubiquitinase inhibition of 19S regulatory particles by 4-arylidene curcumin analog AC17 causes NF-κB inhibition and p53 reactivation in human lung cancer cells.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_cAug 2013
300 _a1381-92 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCurcumin
_xanalogs & derivatives
650 0 4 _aDisease Models, Animal
650 0 4 _aEnzyme Activation
_xdrug effects
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aNF-kappa B
_xantagonists & inhibitors
650 0 4 _aProteasome Endopeptidase Complex
_xmetabolism
650 0 4 _aProteasome Inhibitors
_xpharmacology
650 0 4 _aProteolysis
_xdrug effects
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aTumor Suppressor Protein p53
_xagonists
650 0 4 _aUbiquitin-Specific Proteases
_xantagonists & inhibitors
650 0 4 _aUbiquitination
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aZuo, Yinglin
700 1 _aLi, Baojian
700 1 _aWang, Hao
700 1 _aLiu, Hao
700 1 _aWang, Xianfeng
700 1 _aQiu, Xu
700 1 _aHu, Yun
700 1 _aWen, Shijun
700 1 _aDu, Jun
700 1 _aBu, Xianzhang
773 0 _tMolecular cancer therapeutics
_gvol. 12
_gno. 8
_gp. 1381-92
856 4 0 _uhttps://doi.org/10.1158/1535-7163.MCT-12-1057
_zAvailable from publisher's website
999 _c22771103
_d22771103