| 000 | 02176 a2200685 4500 | ||
|---|---|---|---|
| 005 | 20250516151359.0 | ||
| 264 | 0 | _c20130903 | |
| 008 | 201309s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm400459m _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aWu, Yulin | |
| 245 | 0 | 0 |
_aDiscovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cJun 2013 |
||
| 300 |
_a5094-114 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBile Acids and Salts _xmetabolism |
| 650 | 0 | 4 |
_aDiabetes Mellitus, Type 2 _xdrug therapy |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDrug Discovery |
| 650 | 0 | 4 | _aDrug Stability |
| 650 | 0 | 4 | _aHEK293 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHypoglycemic Agents _xchemistry |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMethylamines _xchemistry |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 |
_aOrganic Anion Transporters, Sodium-Dependent _xantagonists & inhibitors |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aSolubility |
| 650 | 0 | 4 |
_aSymporters _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aThiazepines _xchemistry |
| 700 | 1 | _aAquino, Christopher J | |
| 700 | 1 | _aCowan, David J | |
| 700 | 1 | _aAnderson, Don L | |
| 700 | 1 | _aAmbroso, Jeff L | |
| 700 | 1 | _aBishop, Michael J | |
| 700 | 1 | _aBoros, Eric E | |
| 700 | 1 | _aChen, Lihong | |
| 700 | 1 | _aCunningham, Alan | |
| 700 | 1 | _aDobbins, Robert L | |
| 700 | 1 | _aFeldman, Paul L | |
| 700 | 1 | _aHarston, Lindsey T | |
| 700 | 1 | _aKaldor, Istvan W | |
| 700 | 1 | _aKlein, Ryan | |
| 700 | 1 | _aLiang, Xi | |
| 700 | 1 | _aMcIntyre, Maggie S | |
| 700 | 1 | _aMerrill, Christine L | |
| 700 | 1 | _aPatterson, Kristin M | |
| 700 | 1 | _aPrescott, Judith S | |
| 700 | 1 | _aRay, John S | |
| 700 | 1 | _aRoller, Shane G | |
| 700 | 1 | _aYao, Xiaozhou | |
| 700 | 1 | _aYoung, Andrew | |
| 700 | 1 | _aYuen, Josephine | |
| 700 | 1 | _aCollins, Jon L | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 56 _gno. 12 _gp. 5094-114 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm400459m _zAvailable from publisher's website |
| 999 |
_c22755864 _d22755864 |
||