000 | 01831 a2200493 4500 | ||
---|---|---|---|
005 | 20250516150635.0 | ||
264 | 0 | _c20140123 | |
008 | 201401s 0 0 eng d | ||
022 | _a1860-7187 | ||
024 | 7 |
_a10.1002/cmdc.201300112 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aEhmke, Veronika | |
245 | 0 | 0 |
_aOptimization of triazine nitriles as rhodesain inhibitors: structure-activity relationships, bioisosteric imidazopyridine nitriles, and X-ray crystal structure analysis with human cathepsin L. _h[electronic resource] |
260 |
_bChemMedChem _cJun 2013 |
||
300 |
_a967-75 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aCathepsin L _xchemistry |
650 | 0 | 4 | _aCrystallography, X-Ray |
650 | 0 | 4 |
_aCysteine Endopeptidases _xmetabolism |
650 | 0 | 4 |
_aCysteine Proteinase Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aImidazoles _xchemical synthesis |
650 | 0 | 4 | _aLigands |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 |
_aNitriles _xchemical synthesis |
650 | 0 | 4 | _aParasitic Sensitivity Tests |
650 | 0 | 4 |
_aPyridines _xchemical synthesis |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aTriazines _xchemical synthesis |
650 | 0 | 4 |
_aTrypanosoma brucei brucei _xdrug effects |
700 | 1 | _aWinkler, Edwin | |
700 | 1 | _aBanner, David W | |
700 | 1 | _aHaap, Wolfgang | |
700 | 1 | _aSchweizer, W Bernd | |
700 | 1 | _aRottmann, Matthias | |
700 | 1 | _aKaiser, Marcel | |
700 | 1 | _aFreymond, Céline | |
700 | 1 | _aSchirmeister, Tanja | |
700 | 1 | _aDiederich, François | |
773 | 0 |
_tChemMedChem _gvol. 8 _gno. 6 _gp. 967-75 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1002/cmdc.201300112 _zAvailable from publisher's website |
999 |
_c22735991 _d22735991 |