| 000 | 01798 a2200529 4500 | ||
|---|---|---|---|
| 005 | 20250516150150.0 | ||
| 264 | 0 | _c20131210 | |
| 008 | 201312s 0 0 eng d | ||
| 022 | _a1520-5126 | ||
| 024 | 7 |
_a10.1021/ja3125417 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aZhao, Yujun | |
| 245 | 0 | 0 |
_aDiastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors. _h[electronic resource] |
| 260 |
_bJournal of the American Chemical Society _cMay 2013 |
||
| 300 |
_a7223-34 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemical synthesis |
| 650 | 0 | 4 |
_aBone Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aBone and Bones _xdrug effects |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 | _aCyclization |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aIndoles _xchemical synthesis |
| 650 | 0 | 4 | _aMice, SCID |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aOsteosarcoma _xdrug therapy |
| 650 | 0 | 4 | _aOxindoles |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins c-mdm2 _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aSpiro Compounds _xchemical synthesis |
| 650 | 0 | 4 | _aStereoisomerism |
| 700 | 1 | _aLiu, Liu | |
| 700 | 1 | _aSun, Wei | |
| 700 | 1 | _aLu, Jianfeng | |
| 700 | 1 | _aMcEachern, Donna | |
| 700 | 1 | _aLi, Xiaoqin | |
| 700 | 1 | _aYu, Shanghai | |
| 700 | 1 | _aBernard, Denzil | |
| 700 | 1 | _aOchsenbein, Philippe | |
| 700 | 1 | _aFerey, Vincent | |
| 700 | 1 | _aCarry, Jean-Christophe | |
| 700 | 1 | _aDeschamps, Jeffrey R | |
| 700 | 1 | _aSun, Duxin | |
| 700 | 1 | _aWang, Shaomeng | |
| 773 | 0 |
_tJournal of the American Chemical Society _gvol. 135 _gno. 19 _gp. 7223-34 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/ja3125417 _zAvailable from publisher's website |
| 999 |
_c22722042 _d22722042 |
||