000 01747 a2200493 4500
005 20250516150006.0
264 0 _c20130530
008 201305s 0 0 eng d
022 _a1476-4687
024 7 _a10.1038/nature12122
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYang, Haijuan
245 0 0 _amTOR kinase structure, mechanism and regulation.
_h[electronic resource]
260 _bNature
_cMay 2013
300 _a217-23 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptor Proteins, Signal Transducing
_xchemistry
650 0 4 _aAdenosine Triphosphate
_xchemistry
650 0 4 _aCatalytic Domain
_xdrug effects
650 0 4 _aCrystallography, X-Ray
650 0 4 _aFurans
_xchemistry
650 0 4 _aHumans
650 0 4 _aIndoles
_xchemistry
650 0 4 _aMagnesium
_xchemistry
650 0 4 _aModels, Molecular
650 0 4 _aNaphthyridines
_xchemistry
650 0 4 _aProtein Structure, Tertiary
_xdrug effects
650 0 4 _aPurines
_xchemistry
650 0 4 _aPyridines
_xchemistry
650 0 4 _aPyrimidines
_xchemistry
650 0 4 _aRibosomal Protein S6 Kinases, 70-kDa
_xmetabolism
650 0 4 _aSirolimus
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTOR Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aTacrolimus Binding Protein 1A
_xchemistry
650 0 4 _amTOR Associated Protein, LST8 Homolog
700 1 _aRudge, Derek G
700 1 _aKoos, Joseph D
700 1 _aVaidialingam, Bhamini
700 1 _aYang, Hyo J
700 1 _aPavletich, Nikola P
773 0 _tNature
_gvol. 497
_gno. 7448
_gp. 217-23
856 4 0 _uhttps://doi.org/10.1038/nature12122
_zAvailable from publisher's website
999 _c22716843
_d22716843