000 02793 a2200829 4500
005 20250516143531.0
264 0 _c20131107
008 201311s 0 0 eng d
022 _a1097-0215
024 7 _a10.1002/ijc.28199
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDai, Congxin
245 0 0 _aPyrimethamine sensitizes pituitary adenomas cells to temozolomide through cathepsin B-dependent and caspase-dependent apoptotic pathways.
_h[electronic resource]
260 _bInternational journal of cancer
_cOct 2013
300 _a1982-93 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents, Alkylating
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCaspase 3
_xmetabolism
650 0 4 _aCaspase 7
_xmetabolism
650 0 4 _aCaspase 9
_xmetabolism
650 0 4 _aCathepsin B
_xbiosynthesis
650 0 4 _aCell Cycle Checkpoints
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCytochromes c
_xmetabolism
650 0 4 _aDNA Damage
650 0 4 _aDacarbazine
_xanalogs & derivatives
650 0 4 _aDrug Synergism
650 0 4 _aFemale
650 0 4 _aFolic Acid Antagonists
_xpharmacology
650 0 4 _aHistones
_xmetabolism
650 0 4 _aLeucovorin
_xpharmacology
650 0 4 _aMatrix Metalloproteinase 2
_xbiosynthesis
650 0 4 _aMatrix Metalloproteinase 9
_xbiosynthesis
650 0 4 _aMice
650 0 4 _aMice, Inbred NOD
650 0 4 _aMice, SCID
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aNeoplasm Invasiveness
650 0 4 _aNeoplasm Transplantation
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aPituitary Neoplasms
_xdrug therapy
650 0 4 _aPoly (ADP-Ribose) Polymerase-1
650 0 4 _aPoly(ADP-ribose) Polymerases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xbiosynthesis
650 0 4 _aPyrimethamine
_xpharmacology
650 0 4 _aRats
650 0 4 _aTemozolomide
650 0 4 _aUp-Regulation
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
650 0 4 _abcl-2-Associated X Protein
_xbiosynthesis
700 1 _aZhang, Bo
700 1 _aLiu, Xiaohai
700 1 _aGuo, Kai
700 1 _aMa, Sihai
700 1 _aCai, Feng
700 1 _aYang, Yakun
700 1 _aYao, Yong
700 1 _aFeng, Ming
700 1 _aBao, Xinjie
700 1 _aDeng, Kan
700 1 _aJiao, Yonghui
700 1 _aWei, Zhenqing
700 1 _aJunji, Wei
700 1 _aXing, Bing
700 1 _aLian, Wei
700 1 _aWang, Renzhi
773 0 _tInternational journal of cancer
_gvol. 133
_gno. 8
_gp. 1982-93
856 4 0 _uhttps://doi.org/10.1002/ijc.28199
_zAvailable from publisher's website
999 _c22648702
_d22648702