000 | 01759 a2200457 4500 | ||
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005 | 20250516142939.0 | ||
264 | 0 | _c20131022 | |
008 | 201310s 0 0 eng d | ||
022 | _a1347-5223 | ||
024 | 7 |
_a10.1248/cpb.c12-00993 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aAbadi, Ashraf Hassan | |
245 | 0 | 0 |
_aModulating the cyclic guanosine monophosphate substrate selectivity of the phosphodiesterase 3 inhibitors by pyridine, pyrido[2,3-d]pyrimidine derivatives and their effects upon the growth of HT-29 cancer cell line. _h[electronic resource] |
260 |
_bChemical & pharmaceutical bulletin _c2013 |
||
300 |
_a405-10 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 | _aCatalytic Domain |
650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
650 | 0 | 4 |
_aCyclic GMP _xmetabolism |
650 | 0 | 4 |
_aCyclic Nucleotide Phosphodiesterases, Type 3 _xchemistry |
650 | 0 | 4 | _aCyclization |
650 | 0 | 4 | _aHT29 Cells |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aHydrolysis |
650 | 0 | 4 | _aMolecular Docking Simulation |
650 | 0 | 4 |
_aPhosphodiesterase 3 Inhibitors _xchemistry |
650 | 0 | 4 | _aProtein Binding |
650 | 0 | 4 |
_aPyridines _xchemistry |
650 | 0 | 4 |
_aPyrimidines _xchemistry |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 | _aSubstrate Specificity |
700 | 1 | _aHany, Marwa Saeed | |
700 | 1 | _aElsharif, Shimaa Awadain | |
700 | 1 | _aEissa, Amal Abdel Haleem | |
700 | 1 | _aGary, Bernard Dewayne | |
700 | 1 | _aTinsley, Heather Nicole | |
700 | 1 | _aPiazza, Gary Anthony | |
773 | 0 |
_tChemical & pharmaceutical bulletin _gvol. 61 _gno. 4 _gp. 405-10 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1248/cpb.c12-00993 _zAvailable from publisher's website |
999 |
_c22631063 _d22631063 |