000 01566 a2200385 4500
005 20250516141930.0
264 0 _c20130702
008 201307s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm301743b
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPirotte, Bernard
245 0 0 _a1,4,2-Benzo/pyridodithiazine 1,1-dioxides structurally related to the ATP-sensitive potassium channel openers 1,2,4-Benzo/pyridothiadiazine 1,1-dioxides exert a myorelaxant activity linked to a distinct mechanism of action.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cApr 2013
300 _a3247-56 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBenzothiadiazines
_xchemical synthesis
650 0 4 _aDiazoxide
_xanalogs & derivatives
650 0 4 _aInsulin-Secreting Cells
_xdrug effects
650 0 4 _aKATP Channels
_xdrug effects
650 0 4 _aMuscle Relaxation
_xdrug effects
650 0 4 _aMuscle, Smooth, Vascular
_xdrug effects
650 0 4 _aParasympatholytics
_xpharmacology
650 0 4 _aStructure-Activity Relationship
650 0 4 _aThiadiazines
_xchemical synthesis
700 1 _ade Tullio, Pascal
700 1 _aFlorence, Xavier
700 1 _aGoffin, Eric
700 1 _aSomers, Fabian
700 1 _aBoverie, Stéphane
700 1 _aLebrun, Philippe
773 0 _tJournal of medicinal chemistry
_gvol. 56
_gno. 8
_gp. 3247-56
856 4 0 _uhttps://doi.org/10.1021/jm301743b
_zAvailable from publisher's website
999 _c22603768
_d22603768