000 01852 a2200529 4500
005 20250516141831.0
264 0 _c20130611
008 201306s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm301882a
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRahman, Khondaker M
245 0 0 _aGC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cApr 2013
300 _a2911-35 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBenzodiazepines
_xchemistry
650 0 4 _aCell Line, Tumor
650 0 4 _aDisease Models, Animal
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aFluorescence Resonance Energy Transfer
650 0 4 _aGC Rich Sequence
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aNF-kappa B
_xantagonists & inhibitors
650 0 4 _aSpectrometry, Mass, Electrospray Ionization
700 1 _aJackson, Paul J M
700 1 _aJames, Colin H
700 1 _aBasu, B Piku
700 1 _aHartley, John A
700 1 _ade la Fuente, Maria
700 1 _aSchatzlein, Andreas
700 1 _aRobson, Mathew
700 1 _aPedley, R Barbara
700 1 _aPepper, Chris
700 1 _aFox, Keith R
700 1 _aHoward, Philip W
700 1 _aThurston, David E
773 0 _tJournal of medicinal chemistry
_gvol. 56
_gno. 7
_gp. 2911-35
856 4 0 _uhttps://doi.org/10.1021/jm301882a
_zAvailable from publisher's website
999 _c22600967
_d22600967