000 01890 a2200469 4500
005 20250516141451.0
264 0 _c20131029
008 201310s 0 0 eng d
022 _a1791-244X
024 7 _a10.3892/ijmm.2013.1303
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCho, Jae-We
245 0 0 _aDownregulation of type I collagen expression in silibinin-treated human skin fibroblasts by blocking the activation of Smad2/3-dependent signaling pathways: potential therapeutic use in the chemoprevention of keloids.
_h[electronic resource]
260 _bInternational journal of molecular medicine
_cMay 2013
300 _a1148-52 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Nucleus
_xdrug effects
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aChemoprevention
650 0 4 _aCollagen Type I
_xgenetics
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aFibroblasts
_xdrug effects
650 0 4 _aHumans
650 0 4 _aKeloid
_xdrug therapy
650 0 4 _aMatrix Metalloproteinases
_xmetabolism
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aPromoter Regions, Genetic
_xgenetics
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSilybin
650 0 4 _aSilymarin
_xpharmacology
650 0 4 _aSkin
_xpathology
650 0 4 _aSmad Proteins
_xmetabolism
650 0 4 _aSmad2 Protein
_xmetabolism
650 0 4 _aSmad3 Protein
_xmetabolism
650 0 4 _aTissue Inhibitor of Metalloproteinase-1
_xmetabolism
650 0 4 _aTransforming Growth Factor beta1
_xpharmacology
700 1 _aIl, Kwon-Jun
700 1 _aLee, Kyu-Suk
773 0 _tInternational journal of molecular medicine
_gvol. 31
_gno. 5
_gp. 1148-52
856 4 0 _uhttps://doi.org/10.3892/ijmm.2013.1303
_zAvailable from publisher's website
999 _c22590680
_d22590680