000 01986 a2200601 4500
005 20250516133557.0
264 0 _c20131021
008 201310s 0 0 eng d
022 _a1476-5551
024 7 _a10.1038/leu.2013.38
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDeAngelo, D J
245 0 0 _aPhase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies.
_h[electronic resource]
260 _bLeukemia
_cAug 2013
300 _a1628-36 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylation
650 0 4 _aAdministration, Oral
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aDrug Administration Schedule
650 0 4 _aFemale
650 0 4 _aHematologic Neoplasms
_xdiagnosis
650 0 4 _aHistone Deacetylase Inhibitors
_xadministration & dosage
650 0 4 _aHistones
_xmetabolism
650 0 4 _aHumans
650 0 4 _aHydroxamic Acids
_xadministration & dosage
650 0 4 _aIndoles
_xadministration & dosage
650 0 4 _aMale
650 0 4 _aMaximum Tolerated Dose
650 0 4 _aMiddle Aged
650 0 4 _aNeoplasm Staging
650 0 4 _aPanobinostat
650 0 4 _aTreatment Outcome
650 0 4 _aYoung Adult
700 1 _aSpencer, A
700 1 _aBhalla, K N
700 1 _aPrince, H M
700 1 _aFischer, T
700 1 _aKindler, T
700 1 _aGiles, F J
700 1 _aScott, J W
700 1 _aParker, K
700 1 _aLiu, A
700 1 _aWoo, M
700 1 _aAtadja, P
700 1 _aMishra, K K
700 1 _aOttmann, O G
773 0 _tLeukemia
_gvol. 27
_gno. 8
_gp. 1628-36
856 4 0 _uhttps://doi.org/10.1038/leu.2013.38
_zAvailable from publisher's website
999 _c22481329
_d22481329