| 000 | 01659 a2200421 4500 | ||
|---|---|---|---|
| 005 | 20250516132629.0 | ||
| 264 | 0 | _c20130702 | |
| 008 | 201307s 0 0 eng d | ||
| 022 | _a0946-1965 | ||
| 024 | 7 |
_a10.5414/CP201798 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aMikami, Akiko | |
| 245 | 0 | 0 |
_aPharmacokinetic model incorporating mechanism-based inactivation of CYP2D6 can explain both non-linear kinetics and drug interactions of paroxetine. _h[electronic resource] |
| 260 |
_bInternational journal of clinical pharmacology and therapeutics _cMay 2013 |
||
| 300 |
_a374-82 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAnti-Arrhythmia Agents _xadministration & dosage |
| 650 | 0 | 4 |
_aAntidepressive Agents _xadministration & dosage |
| 650 | 0 | 4 | _aBiotransformation |
| 650 | 0 | 4 | _aChemistry, Pharmaceutical |
| 650 | 0 | 4 | _aComputer Simulation |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP2D6 _xmetabolism |
| 650 | 0 | 4 | _aCytochrome P-450 CYP2D6 Inhibitors |
| 650 | 0 | 4 | _aDelayed-Action Preparations |
| 650 | 0 | 4 | _aDrug Dosage Calculations |
| 650 | 0 | 4 | _aDrug Interactions |
| 650 | 0 | 4 |
_aEnzyme Inhibitors _xadministration & dosage |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aMetoprolol _xadministration & dosage |
| 650 | 0 | 4 | _aModels, Biological |
| 650 | 0 | 4 | _aNonlinear Dynamics |
| 650 | 0 | 4 |
_aParoxetine _xadministration & dosage |
| 700 | 1 | _aOhtani, Hisakazu | |
| 700 | 1 | _aHori, Satoko | |
| 700 | 1 | _aSawada, Yasufumi | |
| 773 | 0 |
_tInternational journal of clinical pharmacology and therapeutics _gvol. 51 _gno. 5 _gp. 374-82 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.5414/CP201798 _zAvailable from publisher's website |
| 999 |
_c22455385 _d22455385 |
||