000 02113 a2200577 4500
005 20250516132435.0
264 0 _c20130404
008 201304s 0 0 eng d
022 _a1878-3686
024 7 _a10.1016/j.ccr.2012.12.008
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aShackelford, David B
245 0 0 _aLKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin.
_h[electronic resource]
260 _bCancer cell
_cFeb 2013
300 _a143-58 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAMP-Activated Protein Kinases
_xgenetics
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBlotting, Western
650 0 4 _aCarcinoma, Non-Small-Cell Lung
_xdrug therapy
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aEukaryotic Initiation Factor-2
_xgenetics
650 0 4 _aHumans
650 0 4 _aHypoglycemic Agents
_xtherapeutic use
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aMutation
_xgenetics
650 0 4 _aPhenformin
_xtherapeutic use
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins p21(ras)
_xphysiology
650 0 4 _aRNA, Messenger
_xgenetics
650 0 4 _aReal-Time Polymerase Chain Reaction
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
650 0 4 _aTumor Suppressor Protein p53
_xphysiology
700 1 _aAbt, Evan
700 1 _aGerken, Laurie
700 1 _aVasquez, Debbie S
700 1 _aSeki, Atsuko
700 1 _aLeblanc, Mathias
700 1 _aWei, Liu
700 1 _aFishbein, Michael C
700 1 _aCzernin, Johannes
700 1 _aMischel, Paul S
700 1 _aShaw, Reuben J
773 0 _tCancer cell
_gvol. 23
_gno. 2
_gp. 143-58
856 4 0 _uhttps://doi.org/10.1016/j.ccr.2012.12.008
_zAvailable from publisher's website
999 _c22450196
_d22450196