000 02064 a2200529 4500
005 20250516132104.0
264 0 _c20130516
008 201305s 0 0 eng d
022 _a1528-0020
024 7 _a10.1182/blood-2012-10-460832
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aIyengar, Sunil
245 0 0 _aP110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse.
_h[electronic resource]
260 _bBlood
_cMar 2013
300 _a2274-84 p.
_bdigital
500 _aPublication Type: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aClass I Phosphatidylinositol 3-Kinases
650 0 4 _aDNA Mutational Analysis
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aGene Expression Regulation, Enzymologic
_xphysiology
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aHumans
650 0 4 _aLymphoma, Mantle-Cell
_xdrug therapy
650 0 4 _aPhosphatidylinositol 3-Kinases
_xgenetics
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aProtein Kinase Inhibitors
_xadministration & dosage
650 0 4 _aPurines
_xadministration & dosage
650 0 4 _aQuinazolinones
_xadministration & dosage
650 0 4 _aRecurrence
650 0 4 _aSignal Transduction
_xphysiology
650 0 4 _aSubstrate Specificity
650 0 4 _aTreatment Outcome
700 1 _aClear, Andrew
700 1 _aBödör, Csaba
700 1 _aMaharaj, Lenushka
700 1 _aLee, Abigail
700 1 _aCalaminici, Maria
700 1 _aMatthews, Janet
700 1 _aIqbal, Sameena
700 1 _aAuer, Rebecca
700 1 _aGribben, John
700 1 _aJoel, Simon
773 0 _tBlood
_gvol. 121
_gno. 12
_gp. 2274-84
856 4 0 _uhttps://doi.org/10.1182/blood-2012-10-460832
_zAvailable from publisher's website
999 _c22440001
_d22440001