000 01993 a2200529 4500
005 20250516131851.0
264 0 _c20130627
008 201306s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0053155
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSanGiovanni, John Paul
245 0 0 _aDNA sequence variants in PPARGC1A, a gene encoding a coactivator of the ω-3 LCPUFA sensing PPAR-RXR transcription complex, are associated with NV AMD and AMD-associated loci in genes of complement and VEGF signaling pathways.
_h[electronic resource]
260 _bPloS one
_c2013
300 _ae53155 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAnimals
650 0 4 _aCohort Studies
650 0 4 _aComplement System Proteins
_xgenetics
650 0 4 _aFatty Acids, Omega-3
_xmetabolism
650 0 4 _aFemale
650 0 4 _aGene Expression Profiling
650 0 4 _aGene Regulatory Networks
650 0 4 _aHeat-Shock Proteins
_xchemistry
650 0 4 _aHumans
650 0 4 _aMacular Degeneration
_xgenetics
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aNeovascularization, Pathologic
_xgenetics
650 0 4 _aPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
650 0 4 _aPolymorphism, Single Nucleotide
650 0 4 _aRetina
_xmetabolism
650 0 4 _aSignal Transduction
650 0 4 _aTranscription Factors
_xchemistry
650 0 4 _aVascular Endothelial Growth Factor A
_xgenetics
700 1 _aChen, Jing
700 1 _aSapieha, Przemyslaw
700 1 _aAderman, Christopher M
700 1 _aStahl, Andreas
700 1 _aClemons, Traci E
700 1 _aChew, Emily Y
700 1 _aSmith, Lois E H
773 0 _tPloS one
_gvol. 8
_gno. 1
_gp. e53155
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0053155
_zAvailable from publisher's website
999 _c22434886
_d22434886