000 01585 a2200445 4500
005 20250516131433.0
264 0 _c20130708
008 201307s 0 0 eng d
022 _a1944-9917
024 7 _a10.1210/me.2012-1287
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aStrushkevich, Natallia
245 0 0 _aStructural insights into aldosterone synthase substrate specificity and targeted inhibition.
_h[electronic resource]
260 _bMolecular endocrinology (Baltimore, Md.)
_cFeb 2013
300 _a315-24 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAldosterone
_xbiosynthesis
650 0 4 _aBlood Pressure
650 0 4 _aCatalysis
650 0 4 _aCrystallography, X-Ray
650 0 4 _aCytochrome P-450 CYP11B2
_xantagonists & inhibitors
650 0 4 _aDesoxycorticosterone
_xchemistry
650 0 4 _aFadrozole
_xchemistry
650 0 4 _aHumans
650 0 4 _aHypertension
650 0 4 _aModels, Molecular
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aRenin-Angiotensin System
650 0 4 _aSteroid 11-beta-Hydroxylase
_xmetabolism
650 0 4 _aSubstrate Specificity
650 0 4 _aWater-Electrolyte Balance
700 1 _aGilep, Andrei A
700 1 _aShen, Limin
700 1 _aArrowsmith, Cheryl H
700 1 _aEdwards, Aled M
700 1 _aUsanov, Sergey A
700 1 _aPark, Hee-Won
773 0 _tMolecular endocrinology (Baltimore, Md.)
_gvol. 27
_gno. 2
_gp. 315-24
856 4 0 _uhttps://doi.org/10.1210/me.2012-1287
_zAvailable from publisher's website
999 _c22422239
_d22422239