000 02074 a2200529 4500
005 20250516131123.0
264 0 _c20131211
008 201312s 0 0 eng d
022 _a1558-1497
024 7 _a10.1016/j.neurobiolaging.2012.12.005
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGong, Bing
245 0 0 _aNicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models.
_h[electronic resource]
260 _bNeurobiology of aging
_cJun 2013
300 _a1581-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAmyloid Precursor Protein Secretases
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aAspartic Acid Endopeptidases
_xantagonists & inhibitors
650 0 4 _aCells, Cultured
650 0 4 _aCognition Disorders
_xdrug therapy
650 0 4 _aDisease Models, Animal
650 0 4 _aGene Expression Regulation
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Transgenic
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aNiacinamide
_xanalogs & derivatives
650 0 4 _aOrgan Culture Techniques
650 0 4 _aPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
650 0 4 _aPyridinium Compounds
650 0 4 _aTranscription Factors
_xbiosynthesis
650 0 4 _aUp-Regulation
_xdrug effects
700 1 _aPan, Yong
700 1 _aVempati, Prashant
700 1 _aZhao, Wei
700 1 _aKnable, Lindsay
700 1 _aHo, Lap
700 1 _aWang, Jun
700 1 _aSastre, Magdalena
700 1 _aOno, Kenjiro
700 1 _aSauve, Anthony A
700 1 _aPasinetti, Giulio M
773 0 _tNeurobiology of aging
_gvol. 34
_gno. 6
_gp. 1581-8
856 4 0 _uhttps://doi.org/10.1016/j.neurobiolaging.2012.12.005
_zAvailable from publisher's website
999 _c22413079
_d22413079