000 02413 a2200709 4500
005 20250516130201.0
264 0 _c20130812
008 201308s 0 0 eng d
022 _a1949-2553
024 7 _a10.18632/oncotarget.790
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChung, Suyoun
245 0 0 _aDevelopment of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
_h[electronic resource]
260 _bOncotarget
_cDec 2012
300 _a1629-40 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Design
650 0 4 _aFemale
650 0 4 _aHigh-Throughput Screening Assays
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aInjections, Intravenous
650 0 4 _aMCF-7 Cells
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Inbred NOD
650 0 4 _aMice, SCID
650 0 4 _aMicrofilament Proteins
_xmetabolism
650 0 4 _aMolecular Structure
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aNIH 3T3 Cells
650 0 4 _aNaphthyridines
_xadministration & dosage
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aPhosphorylation
650 0 4 _aProteasome Endopeptidase Complex
_xmetabolism
650 0 4 _aProtein Kinase Inhibitors
_xadministration & dosage
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aRNA Interference
650 0 4 _aSmall Molecule Libraries
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTime Factors
650 0 4 _aTransfection
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
650 0 4 _asrc Homology Domains
700 1 _aSuzuki, Hanae
700 1 _aMiyamoto, Takashi
700 1 _aTakamatsu, Naofumi
700 1 _aTatsuguchi, Ayako
700 1 _aUeda, Koji
700 1 _aKijima, Kyoko
700 1 _aNakamura, Yusuke
700 1 _aMatsuo, Yo
773 0 _tOncotarget
_gvol. 3
_gno. 12
_gp. 1629-40
856 4 0 _uhttps://doi.org/10.18632/oncotarget.790
_zAvailable from publisher's website
999 _c22387296
_d22387296