000 01735 a2200481 4500
005 20250516122019.0
264 0 _c20130528
008 201305s 0 0 eng d
022 _a1872-7786
024 7 _a10.1016/j.cbi.2012.10.023
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKirby, Stephen D
245 0 0 _aHuman paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents.
_h[electronic resource]
260 _bChemico-biological interactions
_cMar 2013
300 _a181-5 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAmino Acid Substitution
650 0 4 _aAntidotes
_xmetabolism
650 0 4 _aAryldialkylphosphatase
_xchemistry
650 0 4 _aCatalytic Domain
_xgenetics
650 0 4 _aChemical Warfare Agents
_xclassification
650 0 4 _aHumans
650 0 4 _aHydrolysis
650 0 4 _aKinetics
650 0 4 _aModels, Molecular
650 0 4 _aMutagenesis, Site-Directed
650 0 4 _aMutant Proteins
_xchemistry
650 0 4 _aOrganophosphates
_xmetabolism
650 0 4 _aOrganophosphorus Compounds
_xclassification
650 0 4 _aOrganothiophosphorus Compounds
_xmetabolism
650 0 4 _aParaoxon
_xclassification
650 0 4 _aProtein Engineering
650 0 4 _aRecombinant Proteins
_xchemistry
650 0 4 _aSarin
_xmetabolism
650 0 4 _aSoman
_xmetabolism
650 0 4 _aSubstrate Specificity
700 1 _aNorris, Joseph R
700 1 _aRichard Smith, J
700 1 _aBahnson, Brian J
700 1 _aCerasoli, Douglas M
773 0 _tChemico-biological interactions
_gvol. 203
_gno. 1
_gp. 181-5
856 4 0 _uhttps://doi.org/10.1016/j.cbi.2012.10.023
_zAvailable from publisher's website
999 _c22271709
_d22271709