000 01887 a2200493 4500
005 20250516121700.0
264 0 _c20131119
008 201311s 0 0 eng d
022 _a1432-1041
024 7 _a10.1007/s00228-012-1429-9
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAzuma, Junichi
245 0 0 _aNAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: a randomized controlled trial for pharmacogenetics-based therapy.
_h[electronic resource]
260 _bEuropean journal of clinical pharmacology
_cMay 2013
300 _a1091-101 p.
_bdigital
500 _aPublication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAnimals
650 0 4 _aAntitubercular Agents
_xadverse effects
650 0 4 _aArylamine N-Acetyltransferase
_xgenetics
650 0 4 _aAsian People
_xgenetics
650 0 4 _aChemical and Drug Induced Liver Injury
_xgenetics
650 0 4 _aGenetic Predisposition to Disease
_xgenetics
650 0 4 _aGenotype
650 0 4 _aHumans
650 0 4 _aIsoniazid
_xadverse effects
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aPrecision Medicine
_xmethods
650 0 4 _aTreatment Failure
650 0 4 _aTuberculosis
_xdrug therapy
700 1 _aOhno, Masako
700 1 _aKubota, Ryuji
700 1 _aYokota, Soichiro
700 1 _aNagai, Takayuki
700 1 _aTsuyuguchi, Kazunari
700 1 _aOkuda, Yasuhisa
700 1 _aTakashima, Tetsuya
700 1 _aKamimura, Sayaka
700 1 _aFujio, Yasushi
700 1 _aKawase, Ichiro
773 0 _tEuropean journal of clinical pharmacology
_gvol. 69
_gno. 5
_gp. 1091-101
856 4 0 _uhttps://doi.org/10.1007/s00228-012-1429-9
_zAvailable from publisher's website
999 _c22262254
_d22262254