000 01965 a2200553 4500
005 20250516121638.0
264 0 _c20130311
008 201303s 0 0 eng d
022 _a1873-5835
024 7 _a10.1016/j.leukres.2012.10.011
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMpakou, Vassiliki E
245 0 0 _aDasatinib inhibits proliferation and induces apoptosis in the KASUMI-1 cell line bearing the t(8;21)(q22;q22) and the N822K c-kit mutation.
_h[electronic resource]
260 _bLeukemia research
_cFeb 2013
300 _a175-82 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCaspases
_xmetabolism
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aChromosomes, Human, Pair 21
650 0 4 _aChromosomes, Human, Pair 8
650 0 4 _aDasatinib
650 0 4 _aEnzyme Activation
_xdrug effects
650 0 4 _aHumans
650 0 4 _aK562 Cells
650 0 4 _aLeukemia, Myeloid, Acute
_xgenetics
650 0 4 _aMutation
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Isoforms
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-akt
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-kit
_xgenetics
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aThiazoles
_xpharmacology
650 0 4 _aTranslocation, Genetic
650 0 4 _asrc-Family Kinases
_xantagonists & inhibitors
700 1 _aKontsioti, Frieda
700 1 _aPapageorgiou, Sotiris
700 1 _aSpathis, Aris
700 1 _aKottaridi, Christine
700 1 _aGirkas, Kostas
700 1 _aKarakitsos, Petros
700 1 _aDimitriadis, George
700 1 _aDervenoulas, Ioannis
700 1 _aPappa, Vasiliki
773 0 _tLeukemia research
_gvol. 37
_gno. 2
_gp. 175-82
856 4 0 _uhttps://doi.org/10.1016/j.leukres.2012.10.011
_zAvailable from publisher's website
999 _c22261230
_d22261230