000			01929 a2200493 4500
005			20250516121300.0
264		0	_c20130712
008			201307s 0 0 eng d
022			_a1521-009X
024	7		_a10.1124/dmd.112.049460 _2doi
040			_aNLM _beng _cNLM
100	1		_aKudo, Toshiyuki
245	0	0	_aAnalysis of the repaglinide concentration increase produced by gemfibrozil and itraconazole based on the inhibition of the hepatic uptake transporter and metabolic enzymes. _h[electronic resource]
260			_bDrug metabolism and disposition: the biological fate of chemicals _cFeb 2013
300			_a362-71 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aArea Under Curve
650	0	4	_aAryl Hydrocarbon Hydroxylases _xantagonists & inhibitors
650	0	4	_aBiotransformation
650	0	4	_aCarbamates _xblood
650	0	4	_aComputer Simulation
650	0	4	_aCytochrome P-450 CYP2C8
650	0	4	_aCytochrome P-450 CYP3A _xmetabolism
650	0	4	_aCytochrome P-450 CYP3A Inhibitors
650	0	4	_aDrug Interactions
650	0	4	_aEnzyme Inhibitors _xblood
650	0	4	_aGemfibrozil _xblood
650	0	4	_aGlucuronides _xpharmacology
650	0	4	_aHumans
650	0	4	_aHypoglycemic Agents _xblood
650	0	4	_aItraconazole _xblood
650	0	4	_aLeast-Squares Analysis
650	0	4	_aLiver _xdrug effects
650	0	4	_aLiver-Specific Organic Anion Transporter 1
650	0	4	_aModels, Biological
650	0	4	_aNonlinear Dynamics
650	0	4	_aOrganic Anion Transporters _xantagonists & inhibitors
650	0	4	_aPiperidines _xblood
700	1		_aHisaka, Akihiro
700	1		_aSugiyama, Yuichi
700	1		_aIto, Kiyomi
773	0		_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 41 _gno. 2 _gp. 362-71
856	4	0	_uhttps://doi.org/10.1124/dmd.112.049460 _zAvailable from publisher's website
999			_c22251940 _d22251940