| 000 | 02859 a2200913 4500 | ||
|---|---|---|---|
| 005 | 20250516120929.0 | ||
| 264 | 0 | _c20130520 | |
| 008 | 201305s 0 0 eng d | ||
| 022 | _a1464-3405 | ||
| 024 | 7 |
_a10.1016/j.bmcl.2012.10.007 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aForsyth, Timothy | |
| 245 | 0 | 0 |
_aSAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry letters _cDec 2012 |
||
| 300 |
_a7653-8 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xadministration & dosage |
| 650 | 0 | 4 |
_aApoptosis _xdrug effects |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 | _aCrystallography, X-Ray |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aHaplorhini |
| 650 | 0 | 4 | _aHigh-Throughput Screening Assays |
| 650 | 0 | 4 |
_aJanus Kinase 2 _xantagonists & inhibitors |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Nude |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 |
_aNeoplasms, Experimental _xdrug therapy |
| 650 | 0 | 4 |
_aProline _xadministration & dosage |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xadministration & dosage |
| 650 | 0 | 4 |
_aPyrimidines _xadministration & dosage |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 | _aXenograft Model Antitumor Assays |
| 700 | 1 | _aKearney, Patrick C | |
| 700 | 1 | _aKim, Byung Gyu | |
| 700 | 1 | _aJohnson, Henry W B | |
| 700 | 1 | _aAay, Naing | |
| 700 | 1 | _aArcalas, Arlyn | |
| 700 | 1 | _aBrown, David S | |
| 700 | 1 | _aChan, Vicky | |
| 700 | 1 | _aChen, Jeff | |
| 700 | 1 | _aDu, Hongwang | |
| 700 | 1 | _aEpshteyn, Sergey | |
| 700 | 1 | _aGalan, Adam A | |
| 700 | 1 | _aHuynh, Tai P | |
| 700 | 1 | _aIbrahim, Mohamed A | |
| 700 | 1 | _aKane, Brian | |
| 700 | 1 | _aKoltun, Elena S | |
| 700 | 1 | _aMann, Grace | |
| 700 | 1 | _aMeyr, Lisa E | |
| 700 | 1 | _aLee, Matthew S | |
| 700 | 1 | _aLewis, Gary L | |
| 700 | 1 | _aNoguchi, Robin T | |
| 700 | 1 | _aPack, Michael | |
| 700 | 1 | _aRidgway, Brian H | |
| 700 | 1 | _aShi, Xian | |
| 700 | 1 | _aTakeuchi, Craig S | |
| 700 | 1 | _aZu, Peiwen | |
| 700 | 1 | _aLeahy, James W | |
| 700 | 1 | _aNuss, John M | |
| 700 | 1 | _aAoyama, Ron | |
| 700 | 1 | _aEngst, Stefan | |
| 700 | 1 | _aGendreau, Steven B | |
| 700 | 1 | _aKassees, Robert | |
| 700 | 1 | _aLi, Jia | |
| 700 | 1 | _aLin, Shwu-Hwa | |
| 700 | 1 | _aMartini, Jean-Francois | |
| 700 | 1 | _aStout, Thomas | |
| 700 | 1 | _aTong, Philip | |
| 700 | 1 | _aWoolfrey, John | |
| 700 | 1 | _aZhang, Wentao | |
| 700 | 1 | _aYu, Peiwen | |
| 773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 22 _gno. 24 _gp. 7653-8 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2012.10.007 _zAvailable from publisher's website |
| 999 |
_c22241097 _d22241097 |
||