| 000 | 01856 a2200505 4500 | ||
|---|---|---|---|
| 005 | 20250516120158.0 | ||
| 264 | 0 | _c20130205 | |
| 008 | 201302s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm3010477 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aWilhelm, Adriana | |
| 245 | 0 | 0 |
_a2-(3-Oxo-1,3-diphenylpropyl)malonic acids as potent allosteric ligands of the PIF pocket of phosphoinositide-dependent kinase-1: development and prodrug concept. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cNov 2012 |
||
| 300 |
_a9817-30 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAllosteric Site |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 |
_aDNA Helicases _xantagonists & inhibitors |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 | _aEnzyme Activation |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aImmunoblotting |
| 650 | 0 | 4 |
_aMalonates _xchemical synthesis |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 |
_aMuscle Cells _xdrug effects |
| 650 | 0 | 4 |
_aProdrugs _xchemical synthesis |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xchemical synthesis |
| 650 | 0 | 4 |
_aProtein Serine-Threonine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 | _aPyruvate Dehydrogenase Acetyl-Transferring Kinase |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aLopez-Garcia, Laura A | |
| 700 | 1 | _aBusschots, Katrien | |
| 700 | 1 | _aFröhner, Wolfgang | |
| 700 | 1 | _aMaurer, Frauke | |
| 700 | 1 | _aBoettcher, Stefan | |
| 700 | 1 | _aZhang, Hua | |
| 700 | 1 | _aSchulze, Jörg O | |
| 700 | 1 | _aBiondi, Ricardo M | |
| 700 | 1 | _aEngel, Matthias | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 55 _gno. 22 _gp. 9817-30 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm3010477 _zAvailable from publisher's website |
| 999 |
_c22220409 _d22220409 |
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