000 01771 a2200541 4500
005 20250516114151.0
264 0 _c20130429
008 201304s 0 0 eng d
022 _a1860-7187
024 7 _a10.1002/cmdc.201200406
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aProvins, Laurent
245 0 0 _aLead optimization of thiazolo[5,4-c]piperidines: 3-cyclobutoxy linker as a key spacer for H(3)R inverse agonists.
_h[electronic resource]
260 _bChemMedChem
_cDec 2012
300 _a2087-92 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBenzamides
_xchemistry
650 0 4 _aCaco-2 Cells
650 0 4 _aHistamine Agonists
_xchemistry
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aPiperidines
_xchemistry
650 0 4 _aRats
650 0 4 _aRats, Wistar
650 0 4 _aReceptors, Histamine H3
_xmetabolism
650 0 4 _aStructure-Activity Relationship
650 0 4 _aThiazoles
_xchemistry
650 0 4 _aTrans-Activators
_xmetabolism
650 0 4 _aTranscriptional Regulator ERG
700 1 _aDenonne, Frédéric
700 1 _aCélanire, Sylvain
700 1 _aChristophe, Bernard
700 1 _aDefays, Sabine
700 1 _aDelaunoy, Christel
700 1 _aDelporte, Marie-Laure
700 1 _aDemaude, Thierry
700 1 _aDurieu, Véronique
700 1 _aGillard, Michel
700 1 _aHubert, Delphine
700 1 _aLamberty, Yves
700 1 _aLorent, Geneviève
700 1 _aValade, Anne
700 1 _aVanbellinghen, Alain
700 1 _aVan Houtvin, Nathalie
773 0 _tChemMedChem
_gvol. 7
_gno. 12
_gp. 2087-92
856 4 0 _uhttps://doi.org/10.1002/cmdc.201200406
_zAvailable from publisher's website
999 _c22164281
_d22164281