000 02305 a2200649 4500
005 20250516113531.0
264 0 _c20130212
008 201302s 0 0 eng d
022 _a1552-4469
024 7 _a10.1038/nchembio.1085
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWinter, Georg E
245 0 0 _aSystems-pharmacology dissection of a drug synergy in imatinib-resistant CML.
_h[electronic resource]
260 _bNature chemical biology
_cNov 2012
300 _a905-912 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAniline Compounds
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBenzamides
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aDrug Synergism
650 0 4 _aFusion Proteins, bcr-abl
_xantagonists & inhibitors
650 0 4 _aImatinib Mesylate
650 0 4 _aLeukemia, Myelogenous, Chronic, BCR-ABL Positive
_xdrug therapy
650 0 4 _aMice
650 0 4 _aNitriles
_xpharmacology
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProteomics
650 0 4 _aProto-Oncogene Proteins c-myc
_xantagonists & inhibitors
650 0 4 _aPyrazoles
_xpharmacology
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aQuinolines
_xpharmacology
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSystems Biology
700 1 _aRix, Uwe
700 1 _aCarlson, Scott M
700 1 _aGleixner, Karoline V
700 1 _aGrebien, Florian
700 1 _aGridling, Manuela
700 1 _aMüller, André C
700 1 _aBreitwieser, Florian P
700 1 _aBilban, Martin
700 1 _aColinge, Jacques
700 1 _aValent, Peter
700 1 _aBennett, Keiryn L
700 1 _aWhite, Forest M
700 1 _aSuperti-Furga, Giulio
773 0 _tNature chemical biology
_gvol. 8
_gno. 11
_gp. 905-912
856 4 0 _uhttps://doi.org/10.1038/nchembio.1085
_zAvailable from publisher's website
999 _c22145994
_d22145994