| 000 | 01557 a2200397 4500 | ||
|---|---|---|---|
| 005 | 20250516113147.0 | ||
| 264 | 0 | _c20130226 | |
| 008 | 201302s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm3008618 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aMahley, Robert W | |
| 245 | 0 | 0 |
_aSmall-molecule structure correctors target abnormal protein structure and function: structure corrector rescue of apolipoprotein E4-associated neuropathology. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cNov 2012 |
||
| 300 |
_a8997-9008 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review | ||
| 650 | 0 | 4 |
_aAlzheimer Disease _xdrug therapy |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aApolipoprotein E4 _xchemistry |
| 650 | 0 | 4 |
_aBrain Injuries _xmetabolism |
| 650 | 0 | 4 |
_aEndoplasmic Reticulum _xmetabolism |
| 650 | 0 | 4 |
_aGolgi Apparatus _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aLipid Metabolism |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Targeted Therapy |
| 650 | 0 | 4 |
_aNeurons _xmetabolism |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 |
_aProtein Folding _xdrug effects |
| 650 | 0 | 4 | _aProtein Transport |
| 650 | 0 | 4 |
_aProteostasis Deficiencies _xdrug therapy |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aHuang, Yadong | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 55 _gno. 21 _gp. 8997-9008 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm3008618 _zAvailable from publisher's website |
| 999 |
_c22136897 _d22136897 |
||