000			02008 a2200577 4500
005			20250516111708.0
264		0	_c20130801
008			201308s 0 0 eng d
022			_a1432-1041
024	7		_a10.1007/s00228-012-1388-1 _2doi
040			_aNLM _beng _cNLM
100	1		_aFuchs, Ines
245	0	0	_aEffect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity. _h[electronic resource]
260			_bEuropean journal of clinical pharmacology _cMar 2013
300			_a507-13 p. _bdigital
500			_aPublication Type: Comparative Study; Journal Article; Randomized Controlled Trial
650	0	4	_aAdult
650	0	4	_aArea Under Curve
650	0	4	_aBiotransformation
650	0	4	_aCross-Over Studies
650	0	4	_aCytochrome P-450 CYP3A _xbiosynthesis
650	0	4	_aCytochrome P-450 CYP3A Inhibitors
650	0	4	_aDrug Administration Schedule
650	0	4	_aDrug Interactions
650	0	4	_aEnzyme Induction
650	0	4	_aEnzyme Inhibitors _xadministration & dosage
650	0	4	_aGermany
650	0	4	_aHumans
650	0	4	_aHydroxylation
650	0	4	_aHypericum
650	0	4	_aKetoconazole _xadministration & dosage
650	0	4	_aMale
650	0	4	_aMetabolic Clearance Rate
650	0	4	_aMidazolam _xadministration & dosage
650	0	4	_aMiddle Aged
650	0	4	_aPlant Extracts _xadministration & dosage
650	0	4	_aPlants, Medicinal
650	0	4	_aPregnane X Receptor
650	0	4	_aReceptors, Steroid _xdrug effects
650	0	4	_aSubstrate Specificity
650	0	4	_aTranscription, Genetic _xdrug effects
650	0	4	_aYoung Adult
700	1		_aHafner-Blumenstiel, Verena
700	1		_aMarkert, Christoph
700	1		_aBurhenne, Jürgen
700	1		_aWeiss, Johanna
700	1		_aHaefeli, Walter Emil
700	1		_aMikus, Gerd
773	0		_tEuropean journal of clinical pharmacology _gvol. 69 _gno. 3 _gp. 507-13
856	4	0	_uhttps://doi.org/10.1007/s00228-012-1388-1 _zAvailable from publisher's website
999			_c22096196 _d22096196