000 01636 a2200457 4500
005 20250516111703.0
264 0 _c20130404
008 201304s 0 0 eng d
022 _a1550-7416
024 7 _a10.1208/s12248-012-9405-y
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aVélez de Mendizábal, Nieves
245 0 0 _aSemi-mechanistic modeling of the interaction between the central and peripheral effects in the antinociceptive response to lumiracoxib in rats.
_h[electronic resource]
260 _bThe AAPS journal
_cDec 2012
300 _a904-14 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCyclooxygenase 2
_xdrug effects
650 0 4 _aCyclooxygenase 2 Inhibitors
_xadministration & dosage
650 0 4 _aDiclofenac
_xadministration & dosage
650 0 4 _aDisease Models, Animal
650 0 4 _aFemale
650 0 4 _aFormaldehyde
650 0 4 _aInjections
650 0 4 _aInjections, Spinal
650 0 4 _aModels, Biological
650 0 4 _aNonlinear Dynamics
650 0 4 _aPain
_xdrug therapy
650 0 4 _aPain Measurement
650 0 4 _aRats
650 0 4 _aRats, Wistar
650 0 4 _aTime Factors
650 0 4 _aUp-Regulation
_xdrug effects
700 1 _aVásquez-Bahena, Dalia
700 1 _aJiménez-Andrade, Juan M
700 1 _aOrtiz, Mario I
700 1 _aCastañeda-Hernández, Gilberto
700 1 _aTrocóniz, Iñaki F
773 0 _tThe AAPS journal
_gvol. 14
_gno. 4
_gp. 904-14
856 4 0 _uhttps://doi.org/10.1208/s12248-012-9405-y
_zAvailable from publisher's website
999 _c22095902
_d22095902